865-21-4 Vincaleukoblastine

Name: Vincaleukoblastine
Synonyms: Vinblastine(7CI); 1H-Indolizino[8,1-cd]carbazole, vincaleukoblastine deriv.;2H-3,7-Methanoazacycloundecino[5,4-b]indole, vincaleukoblastine deriv.;(+)-Vinblastine; 1H-Indolizino[8,1-cd]carbazole-5-carboxylic acid,4-(acetyloxy)-3a-ethyl-9-[5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-,methyl ester, [3aR-[3aa,4b,5b,5ab,9(3R*,5S*,7R*,9S*),10bR*,13aa]]-; Rozevin; VLB; Valban; Vinblastin; Vincaleucoblastin;Vincaleucoblastine; [3aR-[3aa,4b,5b,5ab,9(3R*,5S*,7R*,9S*),10bR*,13aa]]-Methyl 4-(acetyloxy)-3a-ethyl-9-[5-ethyl-1,4,5,6,7,8,9,10-octahydro-5-hydroxy-9-(methoxycarbonyl)-2H-3,7-methanoazacycloundecino[5,4-b]indol-9-yl]-3a,4,5,5a,6,11,12,13a-octahydro-5-hydroxy-8-methoxy-6-methyl-1H-indolizino[8,1-cd]carbazole-5-carboxylate
CAS Number:865-21-4
Molecular Formula:C46H58 N4 O9
Molecular Weight:811.08
EINECS:212-734-0
Density:1.37 g/cm³
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Safety Description:Human poison by intravenous route. Experimental poison by intraperitoneal route. Human systemic effects by intravenous and ocular routes: visual field changes, conjunctiva irritation and other eye effects, cardiomyopathy including infarction, and changes in bone marrow. Experimental teratogenic and reproductive effects. Questionable carcinogen with experimental tumorigenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x. Used as an antineoplastic agent. See also VINCALEUKOBLASTINE SULFATE (1:1) (SALT).
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